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. Author manuscript; available in PMC: 2011 Jun 28.
Published in final edited form as: Nat Protoc. 2010 Jan 7;5(1):93–121. doi: 10.1038/nprot.2009.203

Figure 1. Overview of the procedure to iteratively reconstruct metabolic networks.

Figure 1

In particular stages 2 to 4 are continuously iterated until model predictions are similar to the phenotypic characteristics of the target organism and/or all experimental data for comparison are exhausted.