Table 3. Comparison of the number of CpG islands identified in the human genome with different methods. (NCBI.36).
| Chromosome 21 | |||||||
| CpGPlot | CpGcluster | CpGProD | CpGIS | PSORL | CPSORL | CPSORL (ALU) | |
| Chromosome Length (bp) | 46,944,329 | ||||||
| Total length of CpG islands | 347,334 | 639,161 | 1,072,192 | 1,280,505 | 1,564,596 | 1,607,472 | 926,178 |
| Number of islands predicted | 973 | 2,703 | 1,091 | 3,704 | 2,648 | 2,813 | 850 |
| Island coverage (%)a | 0.73 | 1.36 | 2.28 | 2.73 | 3.3 | 3.4 | 1.97 |
| Island length (bp) | |||||||
| Average | 357 | 237 | 983 | 346 | 591 | 571 | 1,089 |
| Minimum | 101 | 8 | 500 | 200 | 202 | 202 | 500 |
| Maximum | 3,047 | 3,028 | 6,732 | 1,948 | 4,020 | 4,035 | 4,035 |
| GC-content ± SD (%) | 62.17±0.07 | 65.49±0.07 | 54.49±0.06 | 57.98±0.04 | 53.73±0.05 | 53.72±0.05 | 55.60±0.05 |
| CpG island O/E ratio ±SD | 0.84±0.1 | 0.87±0.3 | 0.63±0.1 | 0.68±0.1 | 0.64±0.08 | 0.65±0.08 | 0.65±0.09 |
SD is the Standard Deviation.
a
Proportion (%) of the chromosome sequence covered by methods.