Table 4.

Comparative Analysis of Body Composition and Plasma Leptin levels between the Sickle Cell Anaemia Patients and Control

^Subjects
			SCA Patients					Control
Parameter	Males Boys	Men	Total	Females Girls	Women	Total	Males Boys	Men	Total	Females Girls	Women	Total
N	(17)	(8)	(25)	(16)	(14)	(30)	(7)	(3)	(10)	(7)	(5)	(12)
Age, yr	8.3 ± 1.4	25.7 ± 1.7	17.1 ± 1.6a	8.7 ± 0.8	23.3 ± 2.2	14.5 ± 2.1	9 ± 0.8	27.2 ± 0.2	10.8 ± 2.0	9.6 ± 1.2	22 ± 2.7	14.8 ± 2.2
Weight, kg	18.2 ± 0.9	35.9 ± 1.2a,b	23.9 ± 1.9	17.6 ± 1.6	41.3 ± 1.4	28.7 ± 2.4	18.2 ± 1.7	60.2 ± 1.5	20.8 ± 3.0	21.8 ± 0.8	49 ± 2.6	33 ± 4.4
BMI, kg/mm2	19 ± 0.4	18 ± 0.2a	18.7 ± 0.3a	18.7 ± 0.4a	19.3 ± 0.3a	19 ± 0.2	20.1 ± 0.4	23 ± 0.6	20.2 ± 0.4	21.8 ± 0.8	20.7 ± 0.7	21.2 ± 0.4
FM, kg	4.6 ± 0.8	8.4 ± 0.5a	5.8 ± 0.5	4 ± 0.3	8.7 ± 0.5	6.2 ± 0.5	4.6 ± 0.5c	19.3 ± 0.5c	5.5 ± 1.0c	6.5 ± 0.7	14.4 ± 0.8	21.3 ± 0.5
Leptin, ug/L	1.9 ± 0.9a,b	2.1 ± 0.07	2 ± 0.07b	3.7 ± 0.3a	2.1 ± 0.7a	4.1 ± 0.3a	2.5 ± 0.05c	2.4 ± 0.09c	2.5 ± 0.05c	10.1 ± 0.6	16.3 ± 1.4	12.7 ± 1.2
Leptin/FM	0.45 ± 0.03a,b	0.26 ± 0.02a,b	0.39 ± 0.04a,b	0.96 ± 0.09a	0.55 ± 0.06a	77 ± 0.06a	0.58 ± 0.05c	0.12 ± 0.004c	0.19 ± 0.06c	1.6 ± 0.1	1.1 ± 0.1	1.4 ± 0.1

Data are mean ± SEM

^aP < 0.05 Significantly different in the same gender by age category [SCA Patients vs. Control (Mann-Whitney U test)]

^bP < 0.05 Significantly different in the between gender by age category in SCA Patients (Mann-Whitney U test)

^cP < 0.05 Significantly different in the between gender by age category in the Control Patients (Mann-Whitney U test)

^Age was set at ≤ 16 years for boy or girls and > 16 years for men or women