Table 1.
Factor | Sample Source | Biomarkers | Ref |
---|---|---|---|
Histopathological factors | Urine, Blood | Amyloid beta peptide | [55,56] |
CSF | Tau protein | [57] | |
CSF | Phosphorylated tau | [58] | |
Genetic factor | Blood,saliva | APOE | [59,60] |
CSF, blood,saliva | APP | [61,62,60] | |
Blood | PS-1 | [63] | |
Blood | PS-2 | [63] | |
Synaptic pathological factor | CSF | ADDL | [39] |
Others | CSF | Somatostatin | [64] |
Blood | Metal ions | [65] |