Skip to main content
. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Hepatology. 2011 Jul;54(1):216–228. doi: 10.1002/hep.24360

Figure 7. Serum ALT levels and CD3+CD8+T cells in BM chimeras.

Figure 7

(A) For these experiments, two different types of BM chimera were set-up, as described in the Materials and Methods. KO/WT: B7-H1 KO BM into irradiated WT mice; WT/KO: WT BM into irradiated B7-H1 KO mice. Liver grafts lacking B7-H1 either on BMDC (KO/WT) or parenchymal cells (e.g. hepatocytes) (WT/KO) were transplanted two months after BM transplantation into WT recipients, and serum ALT levels were assayed 12 hr after reperfusion. No differences were detected between KO/WT and WT/KO grafts (n=3 for each group).

(B) Hepatic NPC were analyzed with flow cytometry at 6 hr after KO/WT or WT/KO to WT LTx. Frequencies of CD3+CD8+ cells, as well as percentages of Annexin V positive cells were similar between the two types of chimeric grafts.