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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Hepatology. 2011 Jul;54(1):319–327. doi: 10.1002/hep.24388

Figure 6. Reduced liver damage and fibrosis in TNFR1 KO mice after bile duct ligation.

Figure 6

H&E staining of liver sections (A) and serum transaminase levels (B) in wild-type and TNFR1-KO mice after BDL. TNF-α (C), MMP-9 and TIMP-1 (D), MMP-2 and pro-Colα1(I) (E), and α-SMA (F) mRNA expression in wild-type and TNFR1-KO livers after BDL. In A, Arrowheads signal bile infarcts. Data are mean±SEM, n=4–5 animals/group, *p≤0.05 vs. wild-type Sham, #p≤0.05 vs. wild-type BDL.