A: Sample ROC curves for CTP delineation of DWI defined core using “A-dc” post-processing software (absolute parameter values only; Red: CBF; Purple: CBV*CBF; Green: CBV, and Blue: MTT). B: Bar graph of AUC (area under curve), sensitivity, and specificity (Y-axis) at the optimal ROC operating point for each CTP parameter and post-processing platform (“A-std”, “A-dc” and “B-std”; X-axis), for delineation of core (“r” = relative).