FIG. 4.

Phospholipid biosynthesis pathway. (a) Gene expression profiles (top: cdsA, bottom: pgsA) and metabolite accumulation profiles (top: unsaturated PGs, bottom: cycropropanated PGs). Metabolite accumulation profiles correspond to average values of each PG group. (b) The biosynthesis pathway from phosphatidic acid to phosphatidylethanolamine or cardiolipin. Metabolite and gene names are inside the squares and beside black solid arrows, respectively. Black solid arrows represent chemical reactions. Arrows beside gene names indicate up and down transcriptional activities through cell growth. Dashed arrows mean the weak expression changes. The red and blue lines between genes and metabolites indicate correlations between genes and unsaturated and cycropropanated PGs, respectively.