Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Obesity-associated immune cell infiltration of adipose tissue. Lean individuals exhibit higher ratios of M2:M1 macrophage, Th1:Th2 T cell, and regulatory:effector T cell. Excessive TG accumulation leads to adipose tissue remodeling, relative hypoxia, and ER stress, which trigger production of chemokines and changes in the above cell ratios, culminating in increased production of proinflammatory adipokines and reduced production of antiinflammatory adipokines.
