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Physical features in individuals with 16p11.2 microduplications. a, b 7-year-old male with epicanthal folds, broad nose, frontal hair whorl, wide mouth and low-set ears. c, d, e Siblings aged 6, 2, and their mother (age 38), all of whom have a 16p11.2 microduplication. Note thin upper lip and prominent forehead
