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. 2011 May 27;39(Web Server issue):W450–W454. doi: 10.1093/nar/gkr310

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© The Author(s) 2011. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — An example of the term search view for the human chemokine receptor 4. In the cloud view, it is immediately clear, by the large font of the terms, that CXCR4 is strongly connected to its ligand CXCL12 and CXCR7, with which it forms a heterodimer (A). Also, CXCR4 is strongly connected to ‘HIV infections’ (category: disease), which is mediated by CXCR4 and to ‘stromal’ cell, to which CXCR4 is linked because of its stromal derived ligand CXCL12. In B an example is shown of the underlying abstracts for the co-occurrences.