Table 1.

Dendritic parameters of LGN relay neurons in normal monkeys, and vehicle-treated (VT) glaucoma and memantine-treated (MT) glaucoma monkeys

	Dendrite complexity, Mean ± SD		Total dendrite length, µm Mean ± SD
Group, ID	Layer 1	Layer 6	Layer 1	Layer 6
Normal
S1	22.3 ± 4.1	22.8 ± 5.7	35.1 ± 6.7	36.4 ± 9.1
S2	22.9 ± 4.9	21.6 ± 4.7	38.5 ± 8.0	31.1 ± 7.4
S4	22.7 ± 4.3	20.2 ± 3.8	37.0 ± 7.2	33.0 ± 6.9
S6	26.2 ± 6.2	20.6 ± 4.4	43.1 ± 10.7	32.7 ± 6.5
S7	23.2 ± 4.8	20.8 ± 5.6	36.2 ± 7.3	37.0 ± 9.1
S10	24.9 ± 4.7	21.3 ± 4.6	41.1 ± 8.3	32.2 ± 7.7
Mean ± SD	23.7 ± 1.5	21.2 ± 0.9	38.5 ± 3.1	33.7 ± 2.4
Vehicle-treated glaucoma
91	11.4 ± 4.7	10.9 ± 4.4	18.4 ± 6.9	16.3 ± 6.1
92	9.5 ± 3.1	9.5 ± 2.9	16.2 ± 5.8	15.0 ± 3.9
93	10.6 ± 3.2	9.4 ± 2.8	16.8 ± 5.5	13.5 ± 4.5
96	10.5 ± 4.2	10.7 ± 3.0	18.7 ± 6.2	18.1 ± 5.4
98	11.7 ± 4.5	12.4 ± 4.5	19.0 ± 7.1	18.0 ± 6.8
105	12.2 ± 5.2	11.7 ± 4.1	19.2 ± 7.2	17.4 ± 6.5
106	12.2 ± 4.6	12.8 ± 4.2	20.1 ± 7.2	18.8 ± 6.8
Mean ± SD	11.2 ± 1.0	11.1 ± 1.3	18.4 ± 1.4	16.7 ± 1.9
P value(a)	< 0.0001	< 0.0001	< 0.0001	< 0.0001
Memantine-treated glaucoma
94	18.2 ± 6.2	14.6 ± 6.0	29.7 ± 8.5	22.6 ± 9.3
95	12.0 ± 3.3	12.6 ± 3.6	21.0 ± 6.4	18.6 ± 5.4
97	15.6 ± 6.9	14.5 ± 4.7	27.4 ± 10.2	24.5 ± 7.2
99	16.4 ± 6.3	15.2 ± 5.1	28.3 ± 9.4	24.0 ± 8.0
100	13.4 ± 3.6	12.8 ± 3.5	21.5 ± 6.4	19.0 ± 5.3
101	10.6 ± 3.7	12.5 ± 3.4	18.3 ± 6.4	19.9 ± 5.2
102	16.6 ± 7.7	16.5 ± 5.7	26.8 ± 12.5	25.7 ± 10.3
107	14.5 ± 5.7	13.6 ± 6.0	23.8 ± 9.2	20.4 ± 8.9
Mean ± SD	14.7 ± 2.5	14.0 ± 1.4	24.6 ± 4.1	21.8 ± 2.7
P value(b)	0.0048	0.0011	0.0022	0.0012

SD = Standard Deviation

^(a)t-test values for comparison between VT glaucoma group and normal group

^(b)t-test values for comparison between MT glaucoma group and VT glaucoma group