Table II.

Haematological & immunological parameters in female carriers

Case	I.1	I.2	I.3	I.7	II.5	II.9	II.25	III.17b	Normal adult range
Age (y)	61	59	56	36	31	27	27	8
Leucocytes a	3.6	4.1	3.7	4.8	6	4	4.5	2.5	4.0-11 * 109/L
Neutrophils	1.5	1.8	1.9	1.5	3.9	2.1	2.4	1.7	2.0-7.0 * 109/L
Monocytes	0.2	0.2	0.2	0.3	0.5	0.2	0.4	0.1	0.2-1.8 * 109/L
Eosinophils	0.0	0.0	0.1	0.1	0.1	0.1	0.2	ND	0.02-0.5 * 109/L
Platelets	135	144	136	121	193	168	158	215	150-400 * 109/L
Lymphocytes	1.9	2.1	1.5	2.9	1.5	1.5	1.5	1.4	1.0-3.0 * 109/L
T-cells (CD3+)	1486	1473	1351	2378	1114	1160	1112	511	900-1700 * 106/L
CD4+	904	973	763	1636	694	551	571	291	700-1100 * 106/L
CD8+	591	536	606	779	399	578	522	185	500-900 * 106/L
CD4/CD8 ratio	1.53	1.81	1.26	2.1	1.74	0.95	1.09	1.57	0.57-2.77
B-cells	255	318	238	419	363	301	335	137	200-400 * 106/L
NK cells	118	173	65	63	153	122	94	94	200-400 * 106/L
IgA	1.45	1.54	1.49	0.77	1.35	1.72	1.27	0.38	0.80-2.80 g/L
X-chromosome inactivation	NS c	NS	NS	NS	skewed	skewed	NS	NS

^adata represent single random values. Values outside the normal range (2.5-97.5% percentile) are bolded.

^bthe normal range for these paediatric cases was obtained from (Bain 1995)

^cNS: not skewed