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. Author manuscript; available in PMC: 2011 Jun 29.
Published in final edited form as: Br J Haematol. 2010 Jul 7;150(4):438–445. doi: 10.1111/j.1365-2141.2010.08265.x

Table IV.

Responses by EBMT Criteria and Other Evidence of Activity.

Category Tanespimycin dose, mg/m2
150 n = 4 220 n = 9 275 n = 3 340 n = 7 420 n = 3 525 n = 3 All dose cohorts N = 29
Minimal response, n (%) 1 (25) 0 0 0 0 0 1 (3)
Stable disease, n (%) 2 (50) 5 (56) 3 (100) 3 (43) 1 (33) 1 (33) 15 (52)
Progression of disease, n (%) 1 (25) 4 (44) 0 3 (43) 2 (67) 1 (33) 11 (38)
Missing, n (%) 0 0 0 1 (14) 0 1 (33) 2 (7)
Decrease in M protein, n 1 0 1 2 0 0 4
Decrease in M spike, % 33 11 20, 11
Decrease in urinary M protein, % 41 12 91, 43

EBMT, the European Group for Blood and Marrow Transplantation.