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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Math Biosci. 2011 Mar 21;231(1):19–38. doi: 10.1016/j.mbs.2011.03.008

Fig. 10.

Fig. 10

System design space for the conventional sigmoid model in Section 6.1. Ratio of primary to alternative flux at the basal steady state as a function of normalized input concentration. Stable steady states with the basal rate of transcription (Regions 1 and 3). Stable steady states with the maximal rate of transcription (Regions 6 and 8). Stable steady state with intermediate rates of transcription (Region 5). Unstable steady state with intermediate rates of transcription that lead to hysteresis (Region 7). The parameters in this case are n = 2 and ρ = 1000.