Table 1.
Bax−/− mice have delayed death following infection with T3D
| T3D dose (PFU) | Mouse genotype | No. of mice surviving/no. infected (%) | MDDa | P valueb |
|---|---|---|---|---|
| 100 | WT | 0/17 (0) | 9.7 ± 0.8 | |
| Bax+/− | 0/25 (0) | 9.7 ± 1.1 | 0.96 | |
| Bax−/− | 3/19 (15.8) | 11.8 ± 1.3c | <0.0001 | |
| 1,000 | WT | 0/6 (0) | 9.3 ± 1.0 | |
| Bax+/− | 0/7 (0) | 8.7 ± 1.0 | 0.28 | |
| Bax−/− | 1/5 (20) | 11.8 ± 2.2 | 0.05 |
a
Excludes survivors. Mean values ± standard deviations are shown.
b
P values are in comparison to values for WT mice.
c
Excludes a mouse that succumbed at 19 dpi.