Table 2.
Prevalence of brain lesions in ferrets at various time points postinfection with highly pathogenic H5N1 influenza virusesa
| Time postinfection | Type(s) of brain lesion (no. of animals affected/no. of animals examined) in ferrets infected with: |
|
|---|---|---|
| HK483b | HK486 | |
| Day 3 | Choroiditis (2/3) | Choroiditis (2/3) |
| Day 6 | Vasculitis (2/3) | Encephalitis (2/3), choroiditis (1/3) |
| Day 12 | Choroiditis (2/3) | Encephalitis (3/3) |
| Mo 1 | Hemorrhage (1/3) | Encephalitis (1/3), choroiditis (1/3) |
| Mo 3 | — (0/3) | Encephalitis (2/3) |
| Mo 6 | Hemorrhage (1/3) | Glial scar (1/2) |
| Mo 9 | — (0/2) | Glial scar (1/2) |
a
Observation period, 9 months.
b
—, no brain lesion was detected.