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. 2011 May;85(10):4772–4782. doi: 10.1128/JVI.02409-10

Table 2.

P values from HIV gene flow analysis between GALT, PBMC, and plasma compartments based on envelope sequences from HIV-infected patients

Sample type Patient no. Sample (nb) P value for sequence comparison with indicated samplea (nb)
JD 01 (3) JD 02 (4) JD 03 (14) JD 04 (6) JD 05 (8) JD 06 (7) BD 02 (8) BD 05 (3)
Plasma 116 PR 01 (3) 1 NS 0.2740 NS 0.2040 NS 0.5650 NS 0.5050 NS 0.4040 NS 0.4500 NS 0.9030 NS
PR 06 (PIc) (13) 0.001** 0.001** 0*** 0*** 0*** 0*** 0*** 0.002**
PR 07 (PI) (4) 0.029* 0.026* 0*** 0.0020** 0.0040** 0.0020** 0.0020** 0.0220*
JD 01 (12) JD 02 (21) JD 03 (14) JD 04 (18) JD 05 (11) BD 01 (19) BD 02 (17) BD 03 (8) BD 04 (4)
134 PR 01 (23) 0*** 0*** 0*** 0*** 0*** 0*** 0*** 0*** 0.0170*
PR 05 (PI) (8) 0*** 0*** 0*** 0*** 0*** 0*** 0*** 0*** 0.0130*
JD 01 (3) JD 02 (4) JD 03 (14) JD 04 (6)
140 PR 01 (2) 0.0210* 0.0070** 0.1120 0.0110*
PR 04 (PI) (17) 0*** 0*** 0*** 0***
JD 01 (3) JD 02 (4) JD 03 (14) JD 04 (6) JD 05 (8) JD 06 (7)
PBMCs 116 BD 02 (8) 0.0210* 0.0020* 0.00*** 0.00*** 0.00*** 0.00***
BD 05 (3) 0.0610 NS 0.0290* 0.0030** 0.0120* 0.0300* 0.0100*
JD 01 (12) JD 02 (21) JD 03 (14) JD 04 (18) JD 05 (11)
134 BD 01 (19) 0.6070 NS 0.0090** 0.3050 NS 0.6710 NS 0.6720 NS
BD 02 (17) 0.6830 NS 0.0140* 0.5340 NS 0.9020 NS 0.4700 NS
BD 03 (8) 0.8370 NS 0.1670 NS 0.5640 NS 0.7220 NS 0.4640 NS
BD 04 (4) 0.5790 NS 0.8240 NS 0.7130 NS 0.6800 NS 0.5300 NS
a

Numbers represent P values from the gene flow analysis from the DnaSp software package using 1,000 permutations. Probability was obtained by the permutation test with 1,000 replicates. NS, not significant; *, 0.01 < P < 0.05; **, 0.001 < P < 0.01; ***, P < 0.001. JD, jejunal proviral sequences; BD, PBMC proviral sequences; PR, plasma viral sequences. Numbers following tissue type indicate time points as shown in Fig. 1.

b

n, total number of clonal sequences in each category.

c

PI, post-therapy interruption time point.