Table 1.
Proteins identified by MS as copurifying with TAP-ICP4
| Protein type and Uniprot designation | Description | Ppro | MWa |
|---|---|---|---|
| Viral proteins | |||
| ICP4_HHV11 | Trans-acting transcriptional protein ICP4-human herpesvirus 1 | 5.57E-11 | 132,843.3 |
| KR1_HHV11 | Serine/threonine-protein kinase-human herpesvirus 1 | 3.32E-04 | 52,834.3 |
| Transcription | |||
| TBP_HUMAN | TATA box-binding protein (TATA box factor) | 1.50E-04 | 37,697.9 |
| TAF9B_HUMAN | Transcription initiation factor TFIID subunit 9B | 4.55E-07 | 27,621.7 |
| TAF6_HUMAN | Transcription initiation factor TFIID subunit 6 | 6.58E-09 | 72,668.2 |
| TAF5_HUMAN | Transcription initiation factor TFIID subunit 5 | 3.38E-07 | 86,829.6 |
| TAF4B_HUMAN | Transcription initiation factor TFIID subunit 4B | 3.54E-07 | 91,090.0 |
| TAF4_HUMAN | Transcription initiation factor TFIID subunit 4 | 6.77E-12 | 110,113.7 |
| TAF3_HUMAN | Transcription initiation factor TFIID subunit 3 | 8.16E-04 | 103,581.1 |
| TAF13_HUMAN | Transcription initiation factor TFIID subunit 13 | 2.24E-06 | 14,287.0 |
| TAF10_HUMAN | Transcription initiation factor TFIID subunit 10 | 7.50E-05 | 21,711.2 |
| MED8_HUMAN | Mediator of RNA polymerase II transcription subunit 8 homolog | 9.78E-04 | 29,079.7 |
| GTF2I_HUMAN | General transcription factor II-I (GTFII-I) (TFII-I) | 1.15E-05 | 112,415.6 |
| Miscellaneous | |||
| WDTC1_HUMAN | WD and tetratricopeptide repeat protein 1 | 8.07E-04 | 75,919.3 |
| TTC17_HUMAN | Tetratricopeptide repeat protein 17 | 3.07E-04 | 129,557.5 |
| TMOD1_HUMAN | Tropomodulin-1 | 7.84E-04 | 40,568.9 |
| ROA1_HUMAN | Heterogeneous nuclear ribonucleoprotein A1 (helix-destabilizing protein) | 1.84E-05 | 38,714.3 |
| RL22_HUMAN | 60S ribosomal protein L22 | 3.22E-07 | 14,655.7 |
| PAWR_HUMAN | PRKC apoptosis WT1 regulator protein | 2.90E-05 | 36,567.2 |
| NUD10_HUMAN | Diphosphoinositol polyphosphate phosphohydrolase 3 alpha | 9.09E-04 | 18,499.8 |
| K1967_HUMAN | Protein KIAA1967 (deleted in breast cancer gene 1 protein) | 2.03E-05 | 102,900.9 |
| HS70L_HUMAN | Heat shock 70-kDa protein 1L (heat shock 70-kDa protein 1-like) | 4.03E-05 | 70,374.6 |
| GFAP_HUMAN | Glial fibrillary acidic protein, astrocyte (GFAP) | 3.09E-06 | 49,879.9 |
| CSK21_HUMAN | Casein kinase II subunit alpha | 3.20E-07 | 45,143.3 |
| CALR_HUMAN | Calreticulin precursor (CRP55) | 9.05E-04 | 48,141.1 |
| Calmodulin binding | |||
| MYLK2_HUMAN | Myosin light chain kinase 2, skeletal/cardiac muscle | 4.75E-04 | 64,553.3 |
| MATR3_HUMAN | Matrin-3-Homo sapiens | 1.11E-05 | 94,622.6 |
| EF1A2_HUMAN | Elongation factor 1-alpha 2 (EF-1-alpha-2) | 9.24E-04 | 50,469.8 |
| EF1A1_HUMAN | Elongation factor 1-alpha 1 (EF-1-alpha-1) | 3.05E-07 | 50,140.5 |
| DCAK1_HUMAN | Serine/threonine-protein kinase DCAMKL1 | 3.03E-04 | 82,223.5 |
| CXB3_HUMAN | Gap junction beta-3 protein (Connexin-31) | 4.18E-04 | 30,817.8 |
| CALM_HUMAN | Calmodulin | 2.83E-05 | 16,706.3 |
| Incorrect MW | |||
| S10A7_HUMAN | Protein S100-A7 (S100 calcium-binding protein A7) | 8.60E-08 | 11,325.7 |
| RYR1_HUMAN | Ryanodine receptor 1 (skeletal muscle-type ryanodine receptor) | 5.38E-04 | 565,179.0 |
| RCOR3_HUMAN | REST corepressor 3 | 6.65E-04 | 55,581.1 |
| RBCC1_HUMAN | RB1-inducible coiled-coil protein 1 | 6.65E-04 | 183,059.0 |
| PRD15_HUMAN | PR domain zinc finger protein 15 | 2.64E-04 | 169,267.5 |
| PI4KA_HUMAN | Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) | 7.84E-04 | 231,289.6 |
| NSN5B_HUMAN | NOL1/NOP2/Sun domain family member 5B | 1.37E-04 | 17,679.2 |
| MAS1L_HUMAN | Mas-related G protein-coupled receptor MRG | 9.85E-04 | 42,410.4 |
| KAC_HUMAN | Ig kappa chain C region | 6.33E-14 | 11,608.8 |
| ITPR2_HUMAN | Inositol 1,4,5-trisphosphate receptor type 2 | 7.70E-06 | 308,075.1 |
| GRB10_HUMAN | Growth factor receptor-bound protein 10 | 1.20E-05 | 67,231.1 |
| F109A_HUMAN | Protein FAM109A | 4.75E-04 | 27,215.1 |
| CO032_HUMAN | Uncharacterized protein C15orf32 | 3.36E-04 | 20,262.4 |
| APTX_HUMAN | Aprataxin | 5.30E-04 | 40,739.8 |
a
MW, molecular weight.