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. 2001 Feb 15;15(4):444–454. doi: 10.1101/gad.846001

Figure 4.

Figure 4

Pdx-1 turns off the expression of markers of regions adjacent to the duodenum. Double in situ hybridization with Pdx-1 in orange (A,B,D,E) and Sox2 in the stomach (A), Hex in the bile duct (B), CdxC (D) and CdxA in the jejunum (E) in blue shows that expression of the latter is either turned off (A,B,E) or down-regulated (D) by ectopically expressed Pdx-1. (C) Sites of normal genes expression. In B, Pdx-1 expression was monitored on adjacent sections (not shown) and occurred where indicated (arrow) in a group of cells leaving the bile duct epithelium. The locations of sections A, B, D, and E are shown in C. Bars, 50 μm (B), 100 μm (A), 200 μm (D,E).