Table 2.
Ch16 minichromosome loss rates
| Genetic background | Loss rate | % division |
|---|---|---|
| Wta | 12/9,947 | 0.12 |
| wpl1Δ | 14/4,931 | 0.28 |
| eso1Δ wpl1Δ | 16/5,324 | 0.30 |
| eso1Δ psm3K105N | NDb | ∼100 |
| eso1Δ psm3K105Nwpl1Δ | 0/2,931 | <0.03 |
| eso1Δ psm3K106N | ND | ∼100 |
| eso1Δ psm3K106Nwpl1Δ | 5/6,054 | 0.08 |
| eso1Δ psm3K105NK106N | 50/2,474 | 2.02c |
| eso1Δ psm3K105NK106Nwpl1Δ | 4/5,694 | 0.07 |
| psm3K105NK106N | 25/7,327 | 0.34 |
| psm3K105NK106Nwpl1Δ | 17/6,370 | 0.27 |
| psm3K105R | 14/5,818 | 0.24 |
| psm3K105Rwpl1Δ | 19/6,250 | 0.30 |
| psm3K106R | 55/7,772 | 0.71c |
| psm3K106Rwpl1Δ | 5/6,911 | 0.07 |
| psm3K105RK106R | 66/8,371 | 0.79c |
| psm3K105RK106Rwpl1Δ | 10/6,392 | 0.16 |
a
Wt, wild type.
b
ND, not determined, since Ch16 could not be maintained in this genetic background. The loss rate is therefore estimated as 100%.
c
Statistically significant compared to wt (P value < 0.0001 by the chi-square test).