Fig. 2.

Genetic relatedness of human and bovine lineages. To deduce the genetic relatedness of the lineage II and lineage I and I/II outbreak isolates, the phylogeny was reconstructed utilizing an SNP library specifically developed for the high-resolution typing of E. coli O157:H7 (Eppinger, Mammel, LeClerc, Cebula, and Ravel, unpublished). SNP discovery detected 298 lineage II-specific SNPs unique to the analyzed bovine strains. The colors blue, brown, and red represent the lineage associations of the analyzed strains.