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Serum neutralizing activity in immunized animals (groups 1, 2, 3, and 4) at the time of challenge, presented as 50% inhibitory dilution (ID50). (A) Neutralizing activity in the presence or absence of complement (+C′ or −C′, respectively). (B) Neutralizing activity in the presence of complement versus plasma viral load at 2 w.p.c. The protected animals (F42 and F44) are denoted by empty symbols.
