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Survival of mice inoculated with reassortant viruses that have pathogenicity equal to or greater than that of the CA04 (H1N1) virus. Groups of 10 mice were inoculated with 104.5 TCID50 of each virus. Survival was monitored daily for 13 days. An asterisk indicates viruses that were more pathogenic than Rg CA04 (H1N1) in vitro. A dagger indicates viruses that were as pathogenic as Rg CA04 (H1N1) in vitro.
