Table 4.

Cellular proteins detected in PRV virions and comparison to other herpesviruses

Protein function and namea	PRVb	HSV-1c	HCMVd	EBVe
Small GTPases
Arf1	+	+
Arf3	+	+
Rab1A	+			+
Rab2A	+	+
Rab6A	+
Rab7A	+	+
Rab14	+
Metabolism
Glutathione S-transferase	+
Long-chain fatty acid CoA ligase 4	+
Thioredoxin	+		+
Chaperone
HSP27	+		+	+
Membrane trafficking and organization	+
Annexin A8	+
Syntaxin-12	+
VAMP3/cellubrevin	+
Cytoskeleton
Alpha-actinin-1	+		+	+
Cofilin-2	+
Destrin	+
Myosin light chain 3	+
Myosin-Ic	+
Radixin	+
Transgelin-2	+		+
WD repeat-containing protein 1	+
RNA bindinge
DEAD box helicase 3	+	+	+
Eukaryotic initiation factor 4A-I	+		+
Eukaryotic translation initiation factor 4H	+	+
Eukaryotic translation initiation factor 5A-1	+
HNRNPA2B1	+
HNRNPF	+
HNRNPK	+
Poly(rC)-binding protein 1	+
HNRNPH3	+
Signaling
14-3-3 protein beta/alpha	+		+
14-3-3 protein epsilon	+	+	+
14-3-3 protein sigma	+
14-3-3 protein theta	+		+
Annexin V	+	+
Calmodulin	+
Casein kinase II subunit alpha	+	+	+
Growth factor receptor-bound protein 2	+
Guanine nucleotide-binding protein subunit alpha-2	+
MAPK1	+
Protein phosphatase PP1-alpha catalytic subunit	+		+
Protein phosphatase PP1-beta catalytic subunit	+
RhoA	+
Cell adhesion
Integrin beta-1	+
Leukocyte surface antigen CD47	+
Cell cycle
Galectin-3	+
Ion channel
Chloride intracellular channel protein 1	+

^aCoA, coenzyme A; HNRNP, heterogeneous nuclear ribonucleoprotein; MAPK, mitogen-activated protein kinase.

^bThis study.

^cReference 83.

^dReference 133.

^eReference 56.