Fig. 7.

Neuropathological changes in an adult FVB/n mouse on day 6 p.i. after i.c. inoculation of 1 × 10⁶ PFU of SAFV. (A) Microglial proliferation and perivascular cuffs in the dentate gyrus of the hippocampus with loss of dentate neurons. (B) Lymphocytic meningeal infiltrates and microglial proliferation in the cerebellar molecular layer (black arrows) without involvement of Purkinje cells. (C) Mild meningitis and lymphocytic infiltration in the anterior white matter of the spinal cord (black arrow), with the anterior horn region spared. The sections were stained with hematoxylin and eosin.