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. 2011 Jul;85(14):6832–6843. doi: 10.1128/JVI.00609-11

Fig. 3.

Fig. 3.

Pathogenicity of chimeric rIBV-NS110-PR8HA or rIBV-NS110-HK68HA in BALB/c mice. (A) Pulmonary replication of chimeric virus in mice. Average lung titers ± standard deviations are depicted. The limit of detection was 5 PFU. Also shown is the percent change in weight following intranasal (i.n.) infection with 10-fold serial dilutions of rIBV-NS110-PR8HA (B) or rIBV-NS110-HK68HA (C), from 1 × 105 PFU to 1 × 102 PFU. Control mice were intranasally infected with 1 × 105 PFU of rWT B/Ya88 virus or mock treated with PBS.