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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Neuroscientist. 2011 Apr 15;17(3):321–336. doi: 10.1177/1073858410384740

Figure 2. Subcellular targeting of PKA and other signaling proteins by AKAPs.

Figure 2

A) Left, schematic representation of different converging signaling pathways leading to adenylyl cyclase production of cAMP and activation of the PKA holoenzyme. Right, schematic regulation of the AKAP-anchored PKA holoenzyme. B) Examples of AKAP organized glutamate receptor and ion channel signaling complexes. Top, AKAP79/150 organized signaling complexes. Bottom, Yotiao, MAP2, and AKAP15/18 organized signaling complexes.