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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Neuroscientist. 2011 Apr 15;17(3):321–336. doi: 10.1177/1073858410384740

Figure 7. AKAP79/150 postsynaptic co-localization with PSD-95 is disrupted following chemical induction of LTD in hippocampal neurons.

Figure 7

A) Immunofluorescent staining for rat AKAP150 (red) and the PSD-95 (green) shows punctate co-localization (yellow in merge panels) along hippocampal neurons dendrites including in dendritic spines in control neurons. B) AKAP150 staining declusters and redistributes away from spines and PSD-95 puncta toward dendrite shafts and the soma 30 minutes following a chemical LTD induction stimulus (25 μM NMDA, 3 minutes). Right hand panels are magnifications of dendrites. See (Smith Gibson and Dell'Acqua 2006) for the original report of these findings.