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Alignment of the RING finger domain of HOS1 with those of animal IAPs. Amino acid residues in black indicate identical matches, and those in gray indicate conserved substitutions. The conserved Cys and His residues of the RING finger are indicated by asterisk marks. A missing Cys residue in HOS1 is indicated by a question mark. GeneBank accession numbers for various IAPs are as follows: Human IAP, AAC83232; Pig IAP, AAC39271; Mouse IAP, AAC42078; Rat IAP, AAG22971; HOS1, AAB87130.
