Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Glomerular gene expression of ET-1, ETA receptor, and ETB receptor did not change after 7 weeks of hyperglycemia. Treatment with either antagonist, ABT-627 or A-182086, significantly suppressed gene expression of all ET-1 system components: ET-1, ETA receptor, and ETB receptor. However, the one exception was that A-182086 significantly decreased ET-1 and ETA receptor gene expression compared with the sham. *, p < 0.05 versus sham; †, p < 0.05 versus HG.
