TABLE 2.
ACHE haplotype reconstruction using five ACHE SNPs (5, 8, 9, 12, and 16)
ACHE haplotypes and diplotypes (diploid haplotypes) in 491 San Diego twins. Haplotype inferences were done in the program Phase <http://depts.washington.edu/ventures/UW_Technology/Express_Licenses/PHASEv2.php>. Nonsynonymous cSNPS: SNP5–R34Q (C/T) SNP9–H353N (G/T); synonymous cSNPs: SNP8–E344E (C/T) SNP12–P477P (C/T); noncoding SNP: SNP16–3′-UTR (C/A).
| Haplotype No. | SNPs 5, 8, 9, 12, and 16 | No. of Chromosomes | Diploid Haploytpe (Diplotype) | No. of Individuals |
|---|---|---|---|---|
| 1 | CCGCC | 891 | 1/1 | 439 |
| 2 | CCGCA | 36 | 1/2 | 1 |
| 3 | CCGTC | 6 | 1/3 | 5 |
| 4 | CCGTA | 15 | 1/6 | 3 |
| 5 | CCTCA | 1 | 1/7 | 1 |
| 6 | CCTTC | 3 | 1/8 | 3 |
| 7 | CCTTA | 26 | 2/2 | 1 |
| 8 | CTGCC | 3 | 2/4 | 10 |
| 9 | TCGCC | 1 | 2/5 | 1 |
| 2/7 | 22 | |||
| 3/9 | 1 | |||
| 4/4 | 2 | |||
| 4/7 | 1 | |||
| 7/7 | 1 |