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Increased GSK-3β inactivation in FXR-KO mice. A, Western blot analysis of total and Ser9-phosphorylated GSK-3β, Ser45-Thr41-phosphorylated β-catenin, and Dvl performed using liver homogenates from WT and FXR-KO mice. B, densitometric analysis of blots in A. Data are expressed as mean ± S.D. Statistical significance: *, P < 0.05; **, P < 0.01.
