Skip to main content
. 2011 Jul;338(1):12–21. doi: 10.1124/jpet.111.179390

Fig. 4.

Fig. 4.

Loss of E-cadherin as a mechanism of β-catenin activation. A, Western blots of E-cadherin and Snail conducted using liver homogenates from WT and FXR-KO mice. B, densitometric analysis of E-cadherin and Snail Western blots. Western blots from three separate mice were scanned and used for the densitometric analysis. Data are expressed as mean ± S.D. Statistical significance: ***, P < 0.001. C, representative photographs of E-cadherin immunohistochemistry on paraffin sections of livers from WT and FXR-KO mice. Arrowheads indicate E-cadherin staining on cell membranes.