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. 2011 Summer;16(2):e5–e10.

Figure 4).

Figure 4)

Effect of 17-β estradiol (E2) on tumour necrosis factor-alpha (TNF-α)-mediated depressive effects on left ventricular contractility and coronary vascular hemodynamics. Data were computed at 60 min recirculation and expressed as mean ± SEM. **P<0.01; ***P<0.001 when compared with control; †††P<0.001 compared with 1 h TNF-α perfusion. 1 h TNF-α 1 h of recirculating TNF-α perfusion; CF Coronary flow; Control 1 h of control perfusion; CVR Coronary vascular resistance; LVEDP Left ventricular end diastolic pressure; Pmax Maximum developed pressure; TNF-α + Est P E2, 0.7 ng/mL of CF; TNF-α + Est T E2, 250 mg/kg rat weight, injected 3 h before the experiment