Figure 2.

Arabidopsis encodes two apparent homologs of the ADA2 proteins of human and yeast. Amino acid sequences for ADA2 homologs from Arabidopsis (a), human (h) and yeast (y) were deduced from cDNA sequences and aligned using the PILEUP program of the GCC sequence analysis package. Amino acids identical in all four sequences are shown as white letters on a black background, whereas amino acids with similar side chains in all four sequences are shown as black letters with a gray background. Three regions of sequence similarity are indicated by black, hatched or gray lines above the sequences, including a Cys-rich region (thick black line) and a myb motif (vertical stripes). Potential nuclear localization signals in both Arabidopsis ADA2 sequences are boxed.