Table 8.
Gold distribution in tissue of male rats after 90-day gold nanoparticle exposure.
| GROUP: (mean ± S.E) | Control | Low | Middle | High |
|---|---|---|---|---|
| Lungs (ng/g) | 14.33 ± 1.25 (5) | 17.41 ± 1.49 (5) | 36.88 ± 1.69 (5) | 2191.77 ± 222.59a (5) |
| Liver (ng/g) | 13.58 ± 0.69 (5) | 13.72 ± 1.26 (5) | 13.77 ± 1.62 (5) | 14.34 ± 1.56 (5) |
| Kidneys (ng/g) | 18.56 ± 1.37 (5) | 21.19 ± 0.75 (5) | 23.13 ± 1.33 (5) | 43.24 ± 2.15a (5) |
| Brain (ng/g) | 17.62 ± 1.71 (5) | 19.77 ± 0.96 (5) | 15.03 ± 1.10 (5) | 17.02 ± 0.94 (5) |
| Olfactory bulb (ng/g) | 11.07 ± 3.88 (8) | 19.22 ± 3.61 (10) | 21.37 ± 3.65 (10) | 16.57 ± 3.47 (8) |
| Blood (ng/ml) | 6.93 ± 0.61 (8) | 5.75 ± 0.73 (10) | 6.41 ± 0.65 (10) | 6.86 ± 0.89 (8) |
( ): number of animals, a: p < 0.01, high group vs. other groups