Table 9.
Gold distribution in tissue of female rats after 90-day gold nanoparticle exposure.
| GROUP: (mean ± S.E) | Control | Low | Middle | High |
|---|---|---|---|---|
| Lungs (ng/g) | 13.75 ± 0.95 (5) | 15.07 ± 2.02 (5) | 28.34 ± 1.16 (5) | 1960.02 ± 92.80a (5) |
| Liver (ng/g) | 16.57 ± 3.89 (5) | 12.08 ± 2.13 (5) | 12.31 ± 1.18 (5) | 14.96 ± 1.54 (5) |
| Kidneys (ng/g) | 21.27 ± 0.65 (5) | 19.43 ± 0.79 (5) | 26.37 ± 0.79 (5) | 61.90 ± 3.15a,** (5) |
| Brain (ng/g) | 19.13 ± 2.31 (5) | 18.42 ± 1.07 (5) | 17.87 ± 0.86 (5) | 22.15 ± 0.75** (5) |
| Olfactory bulb (ng/g) | 23.19 ± 2.45 (10) | 20.22 ± 4.35 (10) | 23.56 ± 4.15 (10) | 22.92 ± 4.07 (10) |
| Blood (ng/ml) | 6.66 ± 0.78 (10) | 6.92 ± 1.08 (10) | 5.10 ± 0.58 (10) | 8.98 ± 1.25 (10) |
( ), number of animals; a, p < 0.01 high group vs. other groups; **, p < 0.01 female rats vs. male rats in high group