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. 2001 Apr 15;15(8):995–1006. doi: 10.1101/gad.873501

Figure 7.

Figure 7

Expression of e4bp4 and dbp in wild-type and mCry1−/−mCry2−/− mice. (A) Expression levels of e4bp4 and dbp in the SCN of wild-type (open bars) and mCry-deficient (solid bars) mice in constant darkness were determined by quantitative in-situ hybridization. The mean peak values of the wild-type mice were adjusted to 100%. Values are expressed as means ± SEM (n = 3). Representative autoradiographs are shown at the top. Because mCry-deficient mice are arrhythmic, we used an environmental time scale (hours in DD) rather than a circadian time scale. *, significant differences in wild-type mice, P < 0.001; there was no significant difference in mCry1−/−mCry2−/− mice. (B) Temporal expression profiles of e4bp4 and dbp in the liver of wild-type and mCry1−/−mCry2−/− mice. Northern blots of the total RNAs (10 μg) prepared from the livers of DD-housed mice are shown. g3pdh was used as a control.