Table 4. Examples of significantly impacted biological pathways in MCF7 cells upon miR-210 overexpression (A) and in MDA-MB-231 cells upon miR-210 repression (B).
A | ||
GO category | Description | LS permutation p value |
GO:0007067 | mitosis | 0.00001 |
GO:0051301 | cell division | 0.00015 |
GO:0043281 | regulation of caspase activity | 0.0002 |
GO:0006916 | anti-apoptosis | 0.00279 |
GO:0002418 | immune response to tumor cell | 0.00501 |
GO:0016337 | cell-cell adhesion | 0.00592 |
GO:0030054 | cell junction | 0.01132 |
GO:0051726 | regulation of cell cycle | 0.01235 |
GO:0045596 | negative regulation of cell differentiation | 0.03377 |
GO:0007346 | regulation of mitotic cell cycle | 0.04383 |
GO:0007160 | cell-matrix adhesion | 0.04499 |
GO:0007093 | mitotic cell cycle checkpoint | 0.04942 |