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. 2011 Jun 29;6(6):e21756. doi: 10.1371/journal.pone.0021756

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Carroll et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A) Mean infectious virus titer in tracheal secretions (TCID₅₀/ml). Inset; mean tracheal secretion peak TCID₅₀ (B) Mean vRNA copy number in tracheal secretions (Log₁₀ copies/ml). Inset; mean tracheal secretion peak vRNA. • No lymphocyte depletion before re-challenge (n = 3) ▪ CD8α⁺ T cell and NK cell depletion before re-challenge (n = 3) ▴ CD20⁺ B cell depletion before re-challenge (n = 3).