Table 3a.
Cognitive performance descriptives and Generalized Estimating Equations results for sons and daughters of LLFS probands or their sibling and their spouse’s controls
| Cognitive test | group | N | Mean | 95%CI | B | 95% CI | p-value |
|---|---|---|---|---|---|---|---|
| Logical Memory IA | LLFS Offspring spouses-controls |
305 | 13.19 | 12.7, 13.7 | 0.13 | −0.56, 0.81 | 0.718 |
| 434 | 13.03 | 12.6, 13.5 | |||||
| Logical Memory IIA | LLFS Offspring spouses-controls |
305 | 11.76 | 11.3, 12.2 | 0.30 | −0.39, 0.99 | 0.391 |
| 434 | 11.47 | 11.0, 11.9 | |||||
| Digit Forward | LLFS Offspring spouses-controls |
305 | 8.55 | 8.3, 8.8 | 0.66 | 0.37, 0.96 | 1.E-05 |
| 434 | 7.83 | 7.6, 8.1 | |||||
| Digit Backward | LLFS Offspring spouses-controls |
305 | 6.76 | 6.5, 7.0 | 0.59 | 0.26, 0.91 | 4.E-04 |
| 434 | 6.17 | 6.0, 6.4 | |||||
| Category Fluency Animals |
LLFS Offspring spouses-controls |
305 | 22.08 | 21.4, 22.8 | −0.31 | −1.21, 0.59 | 0.497 |
| 434 | 22.32 | 21.8, 22.9 | |||||
| Category Fluency Vegetables |
LLFS Offspring spouses-controls |
305 | 15.52 | 15.0, 16.1 | 0.90 | 0.24, 1.56 | 8.E-03 |
| 434 | 14.65 | 14.3, 15.0 |