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(A) Increases in ERK1/2 phosphorylation in undifferentiated and differentiated ATDC5 cells were observed in response to 5μM, 20μM and 50μM of ATP stimulations. (B) Apyrase (10 units/ml) significantly inhibited flow induced ERK1/2 phosphorylation at 5 minutes in both undifferentiated and differentiated ATDC5 cells.
