Table 1.
Host range and cross-species infection of the hepatitis E virus
| HEV strains | Natural host | Susceptible experimental host |
|---|---|---|
| Mammalian HEV | ||
| Genotype 1 | Humans, domestic pigs* | Non-human primates, rats*, lambs*, rabbits* |
| Genotype 2 | Humans | Non-human primate |
| Genotype 3 | Humans, domestic pigs, wild boars, deer, mongoose, rabbits |
Non-human primates, domestic pigs |
| Genotype 4 | Humans, domestic pigs, wild boars, cattle*, sheep* |
Non-human primates, domestic pigs, Balb/C mice*, rabbits* |
| Novel unclassified genotype, Rat HEV |
Rats | Unknown |
| Novel unclassified genotype, Boar HEV |
Wild boars in Japan | Unknown |
| Avian HEV | ||
| Genotype 1 | Chickens (Australia) | Chickens |
| Genotype 2 | Chickens (USA, Canada) | Chickens, Turkeys |
| Genotype 3 | Chickens (Europe, and China) |
*
Reported but not independently confirmed.