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. Author manuscript; available in PMC: 2012 Jan 6.
Published in final edited form as: J Am Chem Soc. 2011 May 4;133(26):9996–9999. doi: 10.1021/ja2022653

Figure 6.

Figure 6

Two monooxygenases, AbeX1 and AbeX2, are responsible for the conversion of an indolocarbazole precursor into the indolotryptoline core of BE-54017. BE-54017 requires three methylations; the exact timing of these transformations is not known.