Table 1.
Clinical characteristics of women in the OPRA cohort
| Variable | Mean | SD | Min | Max |
|---|---|---|---|---|
| Age at baseline (years) | 75.2 | 0.1 | 75.0 | 75.9 |
| Age at 5-year follow-up (years) | 80.2 | 0.2 | 79.6 | 80.9 |
| Weight at baseline (kg) | 67.8 | 11.5 | 41 | 110 |
| Weight at 5-year follow-up (kg) | 66.2 | 11.5 | 34 | 105 |
| Height at age 20 (cm) | 164.1 | 5.5 | 145 | 180 |
| BMD (g/cm2) | ||||
| Femoral neck at baseline | 0.748 | 0.130 | 0.153 | 1.230 |
| Total hip at baseline | 0.849 | 1.149 | 0.498 | 1.416 |
| Lumbar spine at baseline | 0.993 | 0.195 | 0.518 | 1.855 |
| Femoral neck at 5-year follow-up | 0.713 | 0.128 | 0.150 | 1.480 |
| Total hip at 5-year follow-up | 0.800 | 0.140 | 0.260 | 1.390 |
| Lumbar spine at 5-year follow-up | 1.009 | 0.206 | 0.470 | 1.790 |
| Rate of bone loss per year | ||||
| Femoral neck | -1.476 | 2.162 | -13.89 | 7.70 |
| Total hip | -1.230 | 1.868 | -10.39 | 6.33 |
Number of individuals (N) for each phenotype: Age at baseline (BL): 1002, Age at 5 years (y): 753, Weight BL: 1002, Weight 5y: 702, Height at age 20: 958, Femoral neck (FN) BL: 923, Total hip (TH) BL: 902, Lumbar spine (LS) BL: 945, FN 5y: 678, TH 5y: 676, LS 5y: 693, Rate of bone loss (RBL) FN: 655, RBL TH: 638