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Comparison of the AAA3 P-loop sequence in C. elegans and D. melanogaster
| Generic | Worm | Drosophila |
| GxxGxGKT/S | GPPGSGKT (wild-type) | GPAGTGKT (wild-type) |
| ts mutants | GPPESGKT (Schmidt, et al.24) | GPAET GKT (M1) |
| GPPET GKT (M2) | ||
| GPPES GKT (M3) |
Mutations 1–3 were designed to replicate the sequence of the ts mutation published in worm. The amino acid changes produced by the mutations are underlined.
