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Inhibition of F0F1-ATPase by oligomycin inhibits intracellular acidification during apoptosis. The intracellular pH was analyzed at 0, 1, and 2 h after apoptosis induction. All data represent the average (±SE) of at least three independent experiments. To inhibit F0F1-ATPase, 10 μM oligomycin (+oligomycin) was added to the medium 30 min before induction of apoptosis. (A) Rat1a/pBP (vector control) and (B) Rat1a/MyrAkt.
