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. 2011 Mar 1;8(2):270–279. doi: 10.4161/rna.8.2.15013

Figure 3.

Figure 3

Mutations detected in SARS-CoV and S-ExoN Mutants. (A) SARS-CoV genome with nsp14-ExoN in yellow and diamond indication location of ExoN mutant. (B) Mutations identified in 10 SARS-CoV plaque clones (∼320 knt). Legend above indicates type of mutations. (C) Mutations identified in 10 S-ExoN plaque clones (∼320 knt). (D) Representative S-ExoN plaque clones showing unique and shared mutations and patterns. (E) Spike glycoprotein showing the schematic of spike subunits and domains. Lower schematic shows unique mutations across spike from 10 S-ExoN plaque clones (upright-blue) and from population Solexa Sequencing (inverted-black).