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Models of myosin V, VI, and X lever arms. (a) Myosin V has six CaMs bound to IQ motifs that form its lever arm. (b) Myosin X is thought to use its PT and MT domains as stiff SAHs to extend its short LCD and form a longer lever arm. (c and d) The myosin VI lever arm may contain (c) an unfolded TAHB in the PT domain (88) or (d) mainly a stable SAH in the MT domain (87).
